SNORD62B

Across TCGA pan-cancer cohorts, SNORD62B RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of SNORD62B’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where SNORD62B RNA is repressed in tumor relative to normal tissue. In most cancer types SNORD62B is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

BRCA, THCA, and BLCA are the cancer types where SNORD62B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORD62B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−1.045	<.001	6	view →
THCA	All	II,III,IV	−0.948	.001	6	view →
BLCA	Female	All	+1.241	.033	5	view →
KIRC	All	All	+0.464	<.001	4	view →
STAD	Male	II,III,IV	+0.957	.019	3	view →
CHOL	All	All	+1.611	.007	2	view →
READ	All	All	+1.036	.007	2	view →
ESCA	All	All	+0.933	.007	2	view →
KICH	All	II,III,IV	+0.649	.046	1	view →
LIHC	All	II,III,IV	+0.445	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

SNORD62B–BRCA

Open the BRCA breakdown →