small nucleolar RNA, C/D box 62BGenealiases: U62 · U62B
Q-omics provides the consensus-scored SNORD62B profile across patient tissues and cancer cell-line models. SNORD62B expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, SNORD62B is differentially expressed in 10, with the highest sampling consensus in BRCA. Additionally, SNORD62B RNA expression shows 19,292 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, BRCA, and THYM as cancer lineages where SNORD62B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SNORD62B — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SNORD62B survival associations across molecular data types. SNORD62B RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SNORD62B RNA expression–survival associations across cancer types. High SNORD62B expression shows unfavorable associations in KIRC, ACC, COAD and LGG, but favorable associations in UCS and HNSC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .004). Together, the overview and detailed table identify KIRC as the clearest survival context for SNORD62B RNA expression.
This table summarizes SNORD62B tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for SNORD62B. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SNORD62B shows lower tumor expression in BRCA and THCA and higher tumor expression in BLCA, KIRC, STAD and CHOL. The BRCA box plot shows higher SNORD62B RNA expression in normal versus tumor tissue (log2 FC = −1.045, t-test p < 0.001).
This table shows molecular features associated with SNORD62B in patient tissues and cancer cell lines. In patient samples, SNORD62B shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
