small nucleolar RNA, C/D box 60Genealiases: RNU60 · U60
Q-omics provides the consensus-scored SNORD60 profile across patient tissues and cancer cell-line models. SNORD60 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, SNORD60 is differentially expressed in 16, with the highest sampling consensus in COAD. Additionally, SNORD60 RNA expression shows 15,142 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, COAD, and THYM as cancer lineages where SNORD60 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SNORD60 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SNORD60 survival associations across molecular data types. SNORD60 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SNORD60 RNA expression–survival associations across cancer types. High SNORD60 expression shows unfavorable associations in KIRC, ACC, UVM, MESO and COAD, but favorable associations in LUSC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for SNORD60 RNA expression.
This table summarizes SNORD60 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 16. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for SNORD60. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SNORD60 shows higher tumor expression in COAD, STAD, LUSC, LIHC, HNSC and KIRC. The COAD box plot shows higher SNORD60 RNA expression in tumor versus normal tissue (log2 FC = +2.083, t-test p < 0.001).
This table shows molecular features associated with SNORD60 in patient tissues and cancer cell lines. In patient samples, SNORD60 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
