SNORD3B-2

Across TCGA pan-cancer cohorts, SNORD3B-2 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated SNORD3B-2 data layer compared with 1 for mutation status.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SNORD3B-2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SNORD3B-2 expression acts as an unfavorable survival marker, although some lineages such as STAD and HNSC show a favorable association.

STAD, CESC, and KICH are the cancer types where SNORD3B-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	All	0.650	0.390	<.001	102	view →
CESC	OS	Tertile	IV	0.092	0.674	.001	60	view →
KICH	OS	Tertile	II,III,IV	0.690	0.970	.008	39	view →
KIRP	DFS	Tertile	All	0.751	0.892	.005	33	view →
THCA	OS	Tertile	III,IV	0.902	1.000	.003	29	view →
LIHC	OS	Tertile	II,III,IV	0.218	0.582	<.001	28	view →
HNSC	OS	Tertile	II,III,IV	0.467	0.244	.013	21	view →
UVM	DFS	Tertile	II,III,IV	0.252	0.778	<.001	18	view →
BRCA	OS	Quartile	IV	0.413	0.885	.002	16	view →
LGG	DFS	Quartile	All	0.623	0.761	.005	13	view →
BLCA	DFS	Quartile	All	0.654	0.270	.009	12	view →
PAAD	DFS	Quartile	All	0.449	0.179	.024	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

SNORD3B-2–STAD (DFS)

Open the STAD breakdown →