SNORD3B-1

Across TCGA pan-cancer cohorts, SNORD3B-1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated SNORD3B-1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SNORD3B-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORD3B-1 expression acts as an unfavorable survival marker, although some lineages such as THYM and ESCA show a favorable association.

KIRC, KICH, and ACC are the cancer types where SNORD3B-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.519	0.678	<.001	144	view →
KICH	OS	Tertile	All	0.260	0.973	<.001	108	view →
ACC	OS	Quartile	All	0.171	0.854	<.001	63	view →
LIHC	OS	Tertile	II,III,IV	0.309	0.606	.004	25	view →
THCA	DFS	Quartile	III,IV	0.699	0.948	.004	20	view →
THYM	OS	Median	II,III,IV	1.000	0.657	.011	18	view →
KIRP	DFS	Tertile	IV	0.035	0.458	.018	18	view →
ESCA	DFS	Quartile	All	1.000	0.383	.012	18	view →
BLCA	OS	Median	All	0.753	0.671	.013	14	view →
MESO	OS	Quartile	IV	0.868	0.334	.011	9	view →
CESC	DFS	Tertile	III,IV	0.823	0.585	.030	8	view →
LAML	DFS	Quartile	All	0.682	0.464	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

SNORD3B-1–KIRC (DFS)

Open the KIRC breakdown →