SNORD3B-1

Across TCGA pan-cancer cohorts, SNORD3B-1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SNORD3B-1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where SNORD3B-1 RNA is repressed in tumor relative to normal tissue. In most cancer types SNORD3B-1 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.

THCA, LIHC, and KIRP are the cancer types where SNORD3B-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORD3B-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−1.478	<.001	8	view →
LIHC	All	All	+0.081	.003	3	view →
KIRP	All	IV	−0.057	.033	3	view →
UCEC	All	All	+0.480	.040	2	view →
KICH	All	All	−0.285	.009	2	view →
CHOL	All	All	+0.201	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

SNORD3B-1–THCA

Open the THCA breakdown →