Across TCGA pan-cancer cohorts, SNORD28B RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SNORD28B’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where SNORD28B RNA is repressed in tumor relative to normal tissue. In most cancer types SNORD28B is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA are the cancer types where SNORD28B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORD28B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.273	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: SNORD28B RNA expression & survival · all SNORD28B data types