Across TCGA patient cohorts, SNORD116-6 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SNORD116-6-associated genes across cancer lineages are RNA5SP204, MIR515-2, and RPS29P26. Each is linked with SNORD116-6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-6-to-partner and partner-to-SNORD116-6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-6→partner) and Y-score (partner→SNORD116-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP204 →	+0.789	+7.930	<.001	.008	3	1
LUAD	MIR515-2 →	+0.371	+7.930	<.001	.008	3	1
LUAD	RPS29P26 →	+0.463	+7.930	<.001	.008	3	1
LUAD	OR8K4P →	+0.059	+7.930	<.001	.008	3	1
LUAD	MIR6078 →	+0.414	+7.930	<.001	.008	3	1
LUSC	RNU6-989P →	+0.312	+7.924	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

SNORD116-6 survival (RNA) · tumor vs normal (RNA) · all SNORD116-6 data types