SNORD116-4

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SNORD116-4 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SNORD116-4 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher SNORD116-4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD116-4 expression acts as an unfavorable survival marker.

UCS and LGG are the cancer types where SNORD116-4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCSOSMedianAll0.1350.687.00924view →
LGGDFSMedianAll0.2360.728.0333view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SNORD116-4–UCS (OS)

Kaplan–Meier survival curve for SNORD116-4 mutant vs wild-type samples in UCS.

Open the UCS breakdown →

Exploration