SNORD116-30

Across TCGA pan-cancer cohorts, SNORD116-30 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated SNORD116-30 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher SNORD116-30 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD116-30 expression acts as an unfavorable survival marker.

MESO, OV, and DLBC are the cancer types where SNORD116-30 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	IV	0.036	0.602	<.001	81	view →
OV	DFS	Tertile	IV	0.228	0.486	.013	78	view →
DLBC	DFS	Tertile	II,III,IV	0.065	0.829	<.001	54	view →
BLCA	DFS	Tertile	All	0.157	0.505	.002	36	view →
TGCT	DFS	Tertile	II,III,IV	0.618	0.950	.025	36	view →
KIRP	DFS	Tertile	IV	0.088	0.502	<.001	36	view →
UVM	DFS	Tertile	All	0.202	0.784	.002	27	view →
PAAD	DFS	Tertile	All	0.274	0.495	.007	27	view →
CESC	OS	Tertile	IV	0.095	0.592	.004	18	view →
LUAD	DFS	Tertile	IV	0.223	0.710	.043	18	view →
ACC	OS	Tertile	All	0.147	0.685	.018	18	view →
COAD	OS	Tertile	IV	0.045	0.659	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

SNORD116-30–MESO (OS)

Open the MESO breakdown →