SNORD116-3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD116-3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD116-3-associated genes across cancer lineages are NDE1P2, HSD3BP1, and RNU105C. Each is linked with SNORD116-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-3-to-partner and partner-to-SNORD116-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-3→partner) and Y-score (partner→SNORD116-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNDE1P2 →+0.130+5.358<.001.00631
UCECHSD3BP1 →+0.106+5.031.005.00931
UCECRNU105C →+0.338+5.484<.001.00531
UCECRNY3P11 →+0.587+5.484<.001.00531
UCECRNA5SP205 →+0.624+5.852<.001.00331
UCECRNA5SP51 →+1.098+6.582<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration