SNORD116-27

Across TCGA pan-cancer cohorts, SNORD116-27 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SNORD116-27 data layer compared with 15 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher SNORD116-27 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD116-27 expression acts as an unfavorable survival marker.

ESCA and SKCM are the cancer types where SNORD116-27 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	All	0.222	0.680	.031	6	view →
SKCM	OS	Median	All	0.210	0.781	<.001	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SNORD116-27–ESCA (OS)

Open the ESCA breakdown →