SNORD116-26

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SNORD116-26 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated SNORD116-26 data layer compared with 15 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SNORD116-26 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORD116-26 expression acts as an unfavorable survival marker.

COAD are the cancer types where SNORD116-26 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSMedianAll0.1400.783<.00118view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

SNORD116-26–COAD (DFS)

Kaplan–Meier survival curve for SNORD116-26 mutant vs wild-type samples in COAD.

Open the COAD breakdown →

Exploration