Across TCGA patient cohorts, SNORD116-14 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD116-14-associated genes across cancer lineages are MIR5696, MIR1266, and RNU6-993P. Each is linked with SNORD116-14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-14-to-partner and partner-to-SNORD116-14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-14→partner) and Y-score (partner→SNORD116-14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR5696 →	+0.708	+6.123	<.001	.002	3	1
UCEC	MIR1266 →	+0.638	+5.771	<.001	.003	3	1
UCEC	RNU6-993P →	+0.586	+4.982	.002	.009	3	1
SKCM	MIR383 →	+0.443	+7.816	<.001	.008	3	1
SKCM	SNORD114-23 →	+0.447	+7.816	<.001	.008	3	1
SKCM	RNA5SP166 →	+0.328	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

SNORD116-14 survival (RNA) · tumor vs normal (RNA) · all SNORD116-14 data types