Across TCGA patient cohorts, SNORD116-10 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible SNORD116-10-associated genes across cancer lineages are RNU6-471P, RNU6-1258P, and MIR4498. Each is linked with SNORD116-10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-10-to-partner and partner-to-SNORD116-10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-10→partner) and Y-score (partner→SNORD116-10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-471P →	+0.234	+7.930	<.001	.008	3	1
LUAD	RNU6-1258P →	+0.368	+7.930	<.001	.008	3	1
LUAD	MIR4498 →	+0.339	+7.930	<.001	.008	3	1
UCEC	MIR4795 →	+0.386	+4.031	<.001	.003	3	1
UCEC	MIR5091 →	+0.690	+3.640	.006	.008	3	1
UCEC	MIR147A →	+0.269	+4.582	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

SNORD116-10 survival (RNA) · tumor vs normal (RNA) · all SNORD116-10 data types