Across TCGA patient cohorts, SNORD116-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,078 significant associations in total. THCA shows the largest number of these associations.

The most reproducible SNORD116-1-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Nuclear-transcribed mRNA catabolic process, and Regulation of telomere maintenance via telomere lengthening. Each is linked with SNORD116-1 in more than 30 cancer types. Because this analysis shows association rather than direction, both SNORD116-1-to-partner and partner-to-SNORD116-1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-1→partner) and Y-score (partner→SNORD116-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.058	+0.502	.001	.001	3	31
DLBC	Nuclear-transcribed mRNA catabolic process →	+0.070	+0.553	<.001	<.001	3	30
DLBC	Regulation of telomere maintenance via telomere lengthening →	+0.074	+0.763	<.001	<.001	3	29
DLBC	Regulation of DNA biosynthetic process →	+0.058	+0.393	.001	.002	2	30
DLBC	Nuclear export →	+0.068	+0.414	<.001	.001	3	29
DLBC	Transport along microtubule →	+0.042	+0.697	.003	<.001	2	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,078 associations by consensus.

Exploration

SNORD116-1 survival (RNA) · tumor vs normal (RNA) · all SNORD116-1 data types