Across TCGA patient cohorts, SNORD115-6 mutation is significantly associated with the RNA expression of many other genes, with 65 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible SNORD115-6-associated genes across cancer lineages are ZFRP1, RNA5SP291, and MIR4431. Each is linked with SNORD115-6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-6-to-partner and partner-to-SNORD115-6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-6→partner) and Y-score (partner→SNORD115-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ZFRP1 →	+0.013	+5.039	<.001	.003	3	2
LUAD	RNA5SP291 →	+0.552	+7.930	<.001	.008	3	2
LUAD	MIR4431 →	+0.282	+7.930	<.001	.008	3	2
SKCM	OR51C1P →	+0.032	+4.743	<.001	.005	3	2
SKCM	CTBP2P9 →	+0.039	+4.495	<.001	.007	3	1
SKCM	CASKP1 →	+0.161	+4.809	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

Exploration

SNORD115-6 survival (RNA) · tumor vs normal (RNA) · all SNORD115-6 data types