Q-omics provides the consensus-scored SNORD115-46 profile across patient tissues and cancer cell-line models. SNORD115-46 expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in LIHC. Additionally, SNORD115-46 RNA expression shows 2,364 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight LIHC, and ESCA as cancer lineages where SNORD115-46 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes SNORD115-46 survival associations across molecular data types. SNORD115-46 RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

SNORD115-46 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	LIHC (108)	view →

This table ranks reproducible SNORD115-46 RNA expression–survival associations across cancer types. High SNORD115-46 expression shows unfavorable associations in LIHC, LUAD, THCA and LGG, but favorable associations in ESCA. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for SNORD115-46 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.051	0.783	<.001	108	view →
LUAD	OS	Tertile	All	0.223	0.812	<.001	81	view →
THCA	OS	Tertile	III,IV	0.290	0.897	.002	42	view →
LGG	DFS	Tertile	All	0.267	0.742	<.001	42	view →
ESCA	DFS	Tertile	III,IV	1.000	0.281	.043	12	view →

Pink = unfavorable, green = favorable. all 5 lineages →

SNORD115-46-LIHC (OS)

Kaplan–Meier survival curve for SNORD115-46 RNA expression in LIHC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with SNORD115-46 in patient tissues and cancer cell lines. In patient samples, SNORD115-46 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	2,364	ESCA (1095)	view →
Function (RNA)	2,209	STAD (2051)	view →