Across TCGA patient cohorts, SNORD115-42 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-42-associated genes across cancer lineages are OR1AA1P, SLC16A12-AS1, and ARHGAP42P3. Each is linked with SNORD115-42 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-42-to-partner and partner-to-SNORD115-42 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-42→partner) and Y-score (partner→SNORD115-42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR1AA1P →	+0.030	+4.614	.007	.006	3	1
SKCM	SLC16A12-AS1 →	+0.041	+4.884	<.001	.004	3	1
SKCM	ARHGAP42P3 →	+0.011	+5.039	<.001	.003	3	1
SKCM	RCC2P5 →	+0.085	+3.913	<.001	.006	3	1
SKCM	SRIP1 →	+0.129	+4.495	<.001	.007	3	1
UCEC	SNORD115-9 →	+0.612	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

SNORD115-42 survival (RNA) · tumor vs normal (RNA) · all SNORD115-42 data types