Across TCGA pan-cancer cohorts, SNORD115-42 RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated SNORD115-42 data layer compared with 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SNORD115-42 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD115-42 expression acts as an unfavorable survival marker.

LUAD and BRCA are the cancer types where SNORD115-42 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.258	0.787	.018	18	view →
BRCA	DFS	Tertile	II,III,IV	0.222	0.520	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SNORD115-42 tumor-vs-normal RNA expression · all SNORD115-42 data types