Across TCGA patient cohorts, SNORD115-41 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-41-associated genes across cancer lineages are MME-AS1, RPS26P45, and TOMM22P6. Each is linked with SNORD115-41 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-41-to-partner and partner-to-SNORD115-41 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-41→partner) and Y-score (partner→SNORD115-41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MME-AS1 →	+0.243	+3.894	.006	.001	3	1
SKCM	RPS26P45 →	+0.257	+3.636	.002	.003	3	1
SKCM	TOMM22P6 →	+0.056	+4.634	<.001	.003	3	1
UCEC	MIR8088 →	+1.226	+8.066	<.001	.007	3	1
SKCM	MIR6736 →	+0.392	+2.855	.001	.009	3	1
SKCM	KRTAP13-6P →	+0.066	+4.634	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

SNORD115-41 survival (RNA) · tumor vs normal (RNA) · all SNORD115-41 data types