SNORD115-39

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD115-39 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-39-associated genes across cancer lineages are MIR769, MIR3666, and RNA5SP414. Each is linked with SNORD115-39 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-39-to-partner and partner-to-SNORD115-39 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-39→partner) and Y-score (partner→SNORD115-39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMIR769 →+0.243+3.449.004.00932
UCECMIR3666 →+0.502+5.123<.001.00431
UCECRNA5SP414 →+1.449+4.840<.001.00331
SKCMBSN-AS1 →+0.124+3.603<.001.00431
SKCMRN7SL214P →+0.100+4.199<.001.00931
SKCMRN7SL643P →+0.096+4.993<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

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