Across TCGA patient cohorts, SNORD115-33 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-33-associated genes across cancer lineages are RPS24P1, LINC01661, and PHACTR3-AS1. Each is linked with SNORD115-33 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-33-to-partner and partner-to-SNORD115-33 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-33→partner) and Y-score (partner→SNORD115-33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPS24P1 →	+0.895	+5.970	<.001	.002	3	1
SKCM	LINC01661 →	+0.088	+5.097	<.001	.008	3	1
SKCM	PHACTR3-AS1 →	+0.561	+5.224	<.001	.007	3	1
SKCM	RPS23P5 →	+0.201	+5.159	<.001	.007	3	1
SKCM	HMGB4 →	+0.044	+5.436	<.001	.005	3	1
SKCM	OR4C5 →	+0.055	+5.513	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

SNORD115-33 survival (RNA) · tumor vs normal (RNA) · all SNORD115-33 data types