OR4C5

Q-omics provides the consensus-scored OR4C5 profile across patient tissues and cancer cell-line models. OR4C5 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, OR4C5 RNA expression shows 6,319 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, and STAD as cancer lineages where OR4C5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes OR4C5 survival associations across molecular data types. OR4C5 RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

OR4C5 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	KIRC (54)	view →

This table ranks reproducible OR4C5 RNA expression–survival associations across cancer types. High OR4C5 expression shows unfavorable associations in KIRC, GBM, PCPG, LUSC and LUAD, but favorable associations in SKCM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .036). Together, the overview and detailed table identify KIRC as the clearest survival context for OR4C5 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.489	0.655	.036	54	view →
SKCM	DFS	Tertile	II,III,IV	0.631	0.243	.009	36	view →
GBM	DFS	Tertile	All	0.042	0.258	<.001	27	view →
PCPG	DFS	Tertile	All	0.090	0.774	<.001	27	view →
LUSC	OS	Tertile	II,III,IV	0.100	0.780	<.001	24	view →
LUAD	OS	Tertile	All	0.676	0.838	.016	21	view →

Pink = unfavorable, green = favorable. all 12 lineages →

OR4C5-KIRC (DFS)

Explore this curve interactively →