Across TCGA patient cohorts, SNORD115-32 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible SNORD115-32-associated genes across cancer lineages are RNU4-26P, RNU6-492P, and LRRC57P1. Each is linked with SNORD115-32 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-32-to-partner and partner-to-SNORD115-32 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-32→partner) and Y-score (partner→SNORD115-32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	2
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	1
SKCM	LRRC57P1 →	+0.084	+5.362	.005	.005	3	1
SKCM	RN7SL706P →	+0.260	+5.097	<.001	.008	3	1
SKCM	ARL2BPP4 →	+0.126	+5.594	<.001	.004	3	1
HNSC	MIR3683 →	+0.398	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

SNORD115-32 survival (RNA) · tumor vs normal (RNA) · all SNORD115-32 data types