Across TCGA patient cohorts, SNORD115-3 mutation is significantly associated with the RNA expression of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD115-3-associated genes across cancer lineages are NDUFB5P2, RNU1-28P, and MIR6801. Each is linked with SNORD115-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-3-to-partner and partner-to-SNORD115-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-3→partner) and Y-score (partner→SNORD115-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NDUFB5P2 →	+0.089	+4.744	<.001	.001	3	2
UCEC	RNU1-28P →	+0.675	+4.484	<.001	.009	3	2
SKCM	MIR6801 →	+0.589	+4.114	<.001	.005	3	2
UCEC	BNIP3P4 →	+0.172	+4.484	<.001	.009	3	1
UCEC	RNA5SP386 →	+1.050	+5.520	<.001	<.001	3	1
UCEC	MIR6859-2 →	+0.642	+4.690	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

SNORD115-3 survival (RNA) · tumor vs normal (RNA) · all SNORD115-3 data types