SNORD115-26

Across TCGA patient cohorts, SNORD115-26 mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-26-associated genes across cancer lineages are RN7SL794P, MBD3L1, and RNA5SP507. Each is linked with SNORD115-26 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-26-to-partner and partner-to-SNORD115-26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL794P grouped by SNORD115-26-low versus SNORD115-26-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-26→partner) and Y-score (partner→SNORD115-26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL794P →	+0.176	+3.216	<.001	.004	3	2
SKCM	MBD3L1 →	+0.066	+3.180	<.001	.004	3	1
SKCM	RNA5SP507 →	+0.403	+2.992	.005	.006	3	1
SKCM	RNU1-34P →	+0.126	+4.900	<.001	.002	3	1
SKCM	RNU6-32P →	+0.424	+3.135	.001	.004	3	1
SKCM	MIR517B →	+0.257	+4.900	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

RN7SL794P by SNORD115-26 expression — SKCM

Explore this box plot interactively →