SNORD115-25

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD115-25 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-25-associated genes across cancer lineages are BTG3P1, RNA5SP461, and H2AB3. Each is linked with SNORD115-25 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-25-to-partner and partner-to-SNORD115-25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-25→partner) and Y-score (partner→SNORD115-25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMBTG3P1 →+0.089+7.816<.001.00831
SKCMRNA5SP461 →+0.468+7.816<.001.00831
SKCMH2AB3 →+0.109+7.816<.001.00831
SKCMRNU6-839P →+0.458+7.816<.001.00831
SKCMRNU6-1075P →+0.458+7.816<.001.00831
SKCMSNORA35 →+0.404+7.816<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration