SNORD115-22

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD115-22 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-22-associated genes across cancer lineages are LINC02503, RNU6-1018P, and LINC01757. Each is linked with SNORD115-22 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-22-to-partner and partner-to-SNORD115-22 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-22→partner) and Y-score (partner→SNORD115-22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADLINC02503 →+0.089+5.279<.001.00632
LUADRNU6-1018P →+0.688+5.099<.001.00832
SKCMLINC01757 →+0.055+4.495<.001.00732
SKCMBMS1P3 →+0.044+4.884<.001.00431
SKCMRN7SL100P →+0.175+4.947<.001<.00131
SKCMATP5F1AP7 →+0.041+4.825<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration