Across TCGA pan-cancer cohorts, SNORD115-22 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SNORD115-22’s most consistent transcriptional readouts.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where SNORD115-22 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNORD115-22 is over-expressed in tumor.

PRAD are the cancer types where SNORD115-22 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNORD115-22 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PRAD	All	All	+0.060	.042	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: SNORD115-22 RNA expression & survival · all SNORD115-22 data types