SNORD115-18

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD115-18 mutation is significantly associated with the RNA expression of many other genes, with 67 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-18-associated genes across cancer lineages are RPS3AP33, RNU5A-6P, and ARHGAP42P3. Each is linked with SNORD115-18 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-18-to-partner and partner-to-SNORD115-18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-18→partner) and Y-score (partner→SNORD115-18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRPS3AP33 →+0.118+4.109<.001.00432
SKCMRNU5A-6P →+0.196+3.564.001.00532
SKCMARHGAP42P3 →+0.013+5.209<.001<.00131
SKCMMTND3P7 →+0.064+5.488<.001.00131
SKCMRPS27P12 →+0.116+3.508<.001.00631
SKCMRN7SL152P →+0.160+3.725<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

Exploration