Across TCGA pan-cancer cohorts, SNORD115-18 RNA is linked to patient survival in 1 of 34 cancer types, making it a survival-associated SNORD115-18 data layer compared with 3 for mutation status.
The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SNORD115-18 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD115-18 expression acts as an unfavorable survival marker.
STAD are the cancer types where SNORD115-18 RNA most reproducibly stratifies survival.