Across TCGA patient cohorts, SNORD115-16 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible SNORD115-16-associated genes across cancer lineages are RNU2-28P, RNA5SP412, and RNU7-97P. Each is linked with SNORD115-16 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-16-to-partner and partner-to-SNORD115-16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-16→partner) and Y-score (partner→SNORD115-16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU2-28P →	+0.572	+4.233	.003	.009	3	2
UCEC	RNA5SP412 →	+1.351	+4.552	<.001	.005	3	1
SKCM	RNU7-97P →	+0.420	+3.490	<.001	.008	3	1
SKCM	MIR664A →	+0.364	+4.436	<.001	.001	3	1
LUSC	MIR16-2 →	+0.427	+4.191	<.001	.009	3	1
LUSC	RNU6-1084P →	+0.302	+3.694	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration

SNORD115-16 survival (RNA) · tumor vs normal (RNA) · all SNORD115-16 data types