Across TCGA patient cohorts, SNORD115-14 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD115-14-associated genes across cancer lineages are RNU6-162P, MTCO1P43, and OR51F5P. Each is linked with SNORD115-14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-14-to-partner and partner-to-SNORD115-14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-14→partner) and Y-score (partner→SNORD115-14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-162P →	+0.313	+7.954	<.001	.008	3	2
SKCM	MTCO1P43 →	+0.099	+5.328	<.001	.003	3	2
UCEC	OR51F5P →	+0.280	+5.937	<.001	.002	3	1
UCEC	RNA5SP534 →	+0.792	+5.242	<.001	.007	3	1
UCEC	RN7SL820P →	+0.292	+4.982	.001	.009	3	1
SKCM	RPL39P26 →	+0.344	+4.953	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

SNORD115-14 survival (RNA) · tumor vs normal (RNA) · all SNORD115-14 data types