Across TCGA patient cohorts, SNORD115-1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-1-associated genes across cancer lineages are GAPDHP56, PRSS3P1, and RNU6-844P. Each is linked with SNORD115-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-1-to-partner and partner-to-SNORD115-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-1→partner) and Y-score (partner→SNORD115-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GAPDHP56 →	+0.039	+4.594	<.001	.008	3	1
SKCM	PRSS3P1 →	+0.127	+6.021	<.001	<.001	3	1
SKCM	RNU6-844P →	+0.565	+5.508	<.001	<.001	3	1
SKCM	MIR4641 →	+0.565	+4.410	.001	.006	3	1
SKCM	SNORD3P1 →	+0.421	+4.215	<.001	.009	3	1
SKCM	RNA5SP68 →	+0.325	+4.867	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

SNORD115-1 survival (RNA) · tumor vs normal (RNA) · all SNORD115-1 data types