Across TCGA pan-cancer cohorts, SNORD115-1 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated SNORD115-1 data layer.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SNORD115-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD115-1 expression acts as an unfavorable survival marker.
UCEC, THCA, and COAD are the cancer types where SNORD115-1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.