Across TCGA patient cohorts, SNORD114-12 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,000 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible SNORD114-12-associated GO terms across cancer lineages are 'de novo' protein folding, Placenta development, and Stress granule disassembly. Each is linked with SNORD114-12 in more than 8 cancer types. Because this analysis shows association rather than direction, both SNORD114-12-to-partner and partner-to-SNORD114-12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD114-12→partner) and Y-score (partner→SNORD114-12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	'de novo' protein folding →	+0.126	+0.149	<.001	.002	3	9
ESCA	Placenta development →	+0.114	+0.092	<.001	.003	3	6
STAD	Stress granule disassembly →	+0.057	+0.118	<.001	<.001	3	6
ESCA	Regulation of receptor localization to synapse →	+0.099	+0.154	<.001	.006	3	6
ESCA	Protein folding →	+0.133	+0.186	<.001	<.001	3	6
ESCA	Obsolete mitochondrion morphogenesis →	+0.117	+0.136	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,000 associations by consensus.

Exploration

SNORD114-12 survival (RNA) · tumor vs normal (RNA) · all SNORD114-12 data types