SNORD113-5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD113-5 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD113-5-associated genes across cancer lineages are LINC00251, OR1A2, and OR6C76. Each is linked with SNORD113-5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD113-5-to-partner and partner-to-SNORD113-5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00251 grouped by SNORD113-5-low versus SNORD113-5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD113-5→partner) and Y-score (partner→SNORD113-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC00251 →+0.034+5.797<.001.00131
LUADOR1A2 →+0.104+6.197<.001.00131
LUADOR6C76 →+0.082+5.798<.001.00331
LUADRNA5SP443 →+0.385+5.217<.001.00731
LUADMIR629 →+0.553+5.099<.001.00831
LUADRPL32P19 →+0.171+5.410<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

LINC00251 by SNORD113-5 expression — SKCM

Box plot of LINC00251 in SNORD113-5-low vs SNORD113-5-high samples in SKCM.

Explore this box plot interactively →

Exploration