SNORD113-5

Across TCGA pan-cancer cohorts, SNORD113-5 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated SNORD113-5 data layer compared with 2 for mutation status.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SNORD113-5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORD113-5 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

STAD, KICH, and UCEC are the cancer types where SNORD113-5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	All	0.203	0.565	<.001	105	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
UCEC	DFS	Tertile	All	0.674	0.899	<.001	72	view →
ACC	OS	Tertile	All	0.113	0.822	<.001	63	view →
BLCA	OS	Tertile	IV	0.074	0.599	<.001	36	view →
PCPG	DFS	Tertile	All	0.297	0.881	<.001	33	view →
LUSC	DFS	Tertile	III,IV	0.124	0.632	.016	18	view →
PRAD	DFS	Tertile	All	0.135	0.774	.040	18	view →
LGG	OS	Tertile	All	0.557	0.893	.003	6	view →
ESCA	DFS	Tertile	III,IV	0.813	0.289	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

SNORD113-5–STAD (DFS)

Open the STAD breakdown →