SNORA59B

Across TCGA pan-cancer cohorts, SNORA59B RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SNORA59B data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SNORA59B RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SNORA59B expression acts as an unfavorable survival marker, although some lineages such as UCEC and BRCA show a favorable association.

UCEC, READ, and BRCA are the cancer types where SNORA59B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.834	0.569	.001	60	view →
READ	DFS	Tertile	All	0.082	0.799	<.001	45	view →
BRCA	DFS	Tertile	II,III,IV	0.724	0.485	.010	33	view →
HNSC	OS	Tertile	All	0.142	0.435	.004	33	view →
KIRC	OS	Median	All	0.922	0.837	.004	31	view →
LGG	DFS	Tertile	All	0.738	0.854	<.001	30	view →
MESO	OS	Tertile	II,III,IV	0.265	0.440	.015	18	view →
UCS	OS	Tertile	III,IV	0.277	0.609	.044	18	view →
COAD	OS	Tertile	III,IV	0.911	0.481	.017	15	view →
GBM	DFS	Tertile	All	0.338	0.195	.013	9	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	9	view →
STAD	DFS	Tertile	IV	0.137	0.415	.010	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SNORA59B–UCEC (DFS)

Open the UCEC breakdown →