Across TCGA patient cohorts, SNN mutation is significantly associated with the RNA expression of many other genes, with 2,079 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNN-associated genes across cancer lineages are RNU1-17P, MIR7702, and YBX1P9. Each is linked with SNN in more than 1 cancer types. Because this analysis shows association rather than direction, both SNN-to-partner and partner-to-SNN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNN→partner) and Y-score (partner→SNN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-17P →	+0.438	+5.103	<.001	.008	3	2
UCEC	MIR7702 →	+0.202	+4.060	<.001	.006	3	2
CESC	YBX1P9 →	+0.081	+5.010	<.001	.009	3	2
UCEC	RNU6-4P →	+0.504	+2.443	<.001	<.001	3	2
UCEC	DPY19L4P2 →	+0.099	+1.917	<.001	.006	3	2
UCEC	PPIAP27 →	+0.250	+1.936	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,079 associations by consensus.

Exploration

SNN survival (RNA) · tumor vs normal (RNA) · all SNN data types