SNIP1

Across TCGA pan-cancer cohorts, SNIP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SNIP1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SNIP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SNIP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

PDAC, HNSC, and GBM are the cancer types where SNIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	III,IV	0.840	0.444	.018	13	view →
HNSC	DFS	Tertile	III,IV	0.882	1.000	.013	9	view →
GBM	OS	Quartile	All	0.617	0.386	.017	7	view →
LSCC	DFS	Quartile	All	0.851	0.588	.023	6	view →
UCEC	OS	Median	All	0.913	0.989	.049	2	view →
CCRCC	OS	Median	All	0.741	1.000	.027	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SNIP1–PDAC (DFS)

Open the PDAC breakdown →