SNHG22

Across TCGA pan-cancer cohorts, SNHG22 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of SNHG22’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SNHG22 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNHG22 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

KIRC, LIHC, and COAD are the cancer types where SNHG22 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNHG22 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+0.466	<.001	11	view →
LIHC	All	II,III,IV	+0.377	<.001	9	view →
COAD	Female	All	+0.687	<.001	8	view →
THCA	All	II,III,IV	+0.440	<.001	8	view →
HNSC	All	All	+0.108	.007	4	view →
STAD	All	III,IV	+0.598	.037	3	view →
CHOL	Female	All	+0.883	.001	2	view →
READ	All	All	+0.396	.012	2	view →
UCEC	All	All	−0.326	.022	2	view →
KIRP	All	All	+0.284	.001	2	view →
BRCA	All	III,IV	−0.253	.014	2	view →
BLCA	Female	IV	+0.440	.010	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

SNHG22–KIRC

Open the KIRC breakdown →