SNHG1

Across TCGA pan-cancer cohorts, SNHG1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated SNHG1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SNHG1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNHG1 expression acts as an unfavorable survival marker, although some lineages such as UCS and LGG show a favorable association.

ACC, KICH, and LIHC are the cancer types where SNHG1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.180	0.696	<.001	133	view →
KICH	DFS	Tertile	II,III,IV	0.266	1.000	<.001	90	view →
LIHC	DFS	Tertile	All	0.433	0.642	<.001	87	view →
KIRC	DFS	Quartile	II,III,IV	0.340	0.642	<.001	79	view →
UCS	OS	Median	II,III,IV	0.590	0.232	.001	78	view →
KIRP	DFS	Median	All	0.561	0.682	.003	44	view →
LGG	OS	Median	All	0.937	0.849	<.001	36	view →
UCEC	DFS	Median	All	0.794	0.881	.002	34	view →
PRAD	DFS	Median	All	0.668	0.899	<.001	26	view →
THCA	DFS	Quartile	II,III,IV	0.814	0.974	.007	25	view →
READ	OS	Tertile	All	0.754	0.566	.024	17	view →
MESO	DFS	Tertile	IV	0.074	0.504	.002	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

SNHG1–ACC (DFS)

Open the ACC breakdown →