SNHG1

Across TCGA pan-cancer cohorts, SNHG1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of SNHG1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SNHG1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNHG1 is over-expressed in tumor.

BLCA, COAD, and HNSC are the cancer types where SNHG1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNHG1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+2.295	<.001	11	view →
COAD	Female	II,III,IV	+1.845	<.001	11	view →
HNSC	Male	IV	+1.451	<.001	11	view →
KIRC	Male	IV	+1.402	<.001	11	view →
LIHC	Female	II,III,IV	+1.990	<.001	9	view →
LUAD	Male	All	+1.003	<.001	9	view →
LUSC	Male	II,III,IV	+1.941	<.001	8	view →
STAD	All	II,III,IV	+1.159	<.001	7	view →
THCA	Male	All	+0.482	.001	6	view →
CHOL	Female	All	+3.680	<.001	5	view →
READ	Female	All	+1.792	<.001	5	view →
KICH	Male	IV	+1.786	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

SNHG1–BLCA

Open the BLCA breakdown →