SNF8

Across TCGA patient cohorts, SNF8 mutation is significantly associated with the RNA expression of many other genes, with 536 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNF8-associated genes across cancer lineages are LINC02676, LINC01072, and SNRPGP17. Each is linked with SNF8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNF8-to-partner and partner-to-SNF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02676 grouped by SNF8-low versus SNF8-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNF8→partner) and Y-score (partner→SNF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC02676 →	+0.226	+7.741	<.001	.009	3	2
UCEC	LINC01072 →	+0.161	+2.488	<.001	.004	3	2
UCEC	SNRPGP17 →	+0.353	+2.463	<.001	.001	3	1
UCEC	LINC01023 →	+0.916	+3.601	<.001	.001	3	1
UCEC	CHASERR →	+0.592	+2.700	.007	.006	3	1
UCEC	GTSE1-DT →	+0.623	+2.711	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 536 associations by consensus.

LINC02676 by SNF8 expression — COAD

Explore this box plot interactively →