SNCG

Across TCGA patient cohorts, SNCG RNA expression is significantly associated with the protein abundance of many other proteins, with 19,041 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNCG-associated proteins across cancer lineages are SNCG_S124, ADIRF, and PXN. Each is linked with SNCG in more than 8 cancer types. Because this analysis shows association rather than direction, both SNCG-to-partner and partner-to-SNCG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNCG versus SNCG_S124 in BRCA, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNCG→partner) and Y-score (partner→SNCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNCG_S124 →	+1.400	+1.640	<.001	<.001	3	9
BRCA	ADIRF →	+1.358	+2.132	<.001	<.001	3	8
LSCC	PXN →	+0.336	+1.329	<.001	<.001	3	5
LSCC	TINAGL1 →	+0.600	+1.213	<.001	<.001	3	5
GBM	RAVER1 →	-0.286	-1.306	.001	<.001	3	5
BRCA	ELAVL1 →	-0.230	-1.292	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,041 associations by consensus.

SNCG vs SNCG_S124 — BRCA

Explore this scatter interactively →