SNCB

Across TCGA patient cohorts, SNCB RNA expression is significantly associated with the protein abundance of many other proteins, with 16,404 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNCB-associated proteins across cancer lineages are TEP1, TES, and TRAM1. Each is linked with SNCB in more than 3 cancer types. Because this analysis shows association rather than direction, both SNCB-to-partner and partner-to-SNCB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNCB versus TEP1 in GBM, with a Pearson correlation of -0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNCB→partner) and Y-score (partner→SNCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TEP1 →	-0.342	-1.761	<.001	<.001	3	3
GBM	TES →	-0.509	-1.118	<.001	<.001	3	3
PDAC	TRAM1 →	-0.449	-0.230	<.001	.002	3	3
GBM	VAMP8 →	-0.592	-1.142	<.001	<.001	3	3
OV	NCAM1_T798 →	+1.390	+0.436	.001	.006	3	3
LSCC	PPFIA3_S683 →	+0.840	+0.296	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,404 associations by consensus.

SNCB vs TEP1 — GBM

Explore this scatter interactively →