SNCAIP

Across TCGA pan-cancer cohorts, SNCAIP Mutation is linked to patient survival in 10 of 34 cancer types, making it a survival-associated SNCAIP data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SNCAIP Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated SNCAIP expression acts as an unfavorable survival marker, although some lineages such as UCEC and STAD show a favorable association.

UCEC, LUSC, and ESCA are the cancer types where SNCAIP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	1.000	0.429	.003	36	view →
LUSC	OS	Median	II,III,IV	0.263	0.640	<.001	34	view →
ESCA	OS	Median	II,III,IV	0.108	0.703	<.001	30	view →
CHOL	OS	Median	All	0.019	0.800	<.001	24	view →
ACC	OS	Median	All	0.114	0.892	<.001	24	view →
KIRP	OS	Median	II,III,IV	0.148	0.771	<.001	18	view →
COAD	OS	Median	III,IV	0.163	0.791	.004	10	view →
LUAD	DFS	Median	All	0.098	0.768	<.001	9	view →
PRAD	DFS	Median	All	0.148	0.888	<.001	6	view →
STAD	DFS	Median	All	0.887	0.389	.048	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

SNCAIP–UCEC (DFS)

Open the UCEC breakdown →