SNCAIP

Across TCGA pan-cancer cohorts, SNCAIP mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SNCAIP data layer compared with 25 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SNCAIP mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNCAIP expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

PDAC, GBM, and LUAD are the cancer types where SNCAIP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.151	0.872	.024	24	view →
GBM	OS	Quartile	All	0.703	0.428	.003	8	view →
LUAD	DFS	Tertile	All	0.709	0.323	.021	4	view →
LSCC	OS	Median	All	0.606	1.000	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SNCAIP–PDAC (DFS)

Open the PDAC breakdown →